8^th International Conference on Medical Education and Health Sciences 2018-10-08 London ,UK

Biography:

Z S Yahaya has completed his PhD from Ahmadu Bello University Zaria, Nigeria. He is currently working as a Lecturer in the Department of Pharmaceutics, Kaduna State University, Nigeria. He has published more than 5 papers in reputed journals.

Abstract:

The aim of this work was to formulate Artemether, a poorly water soluble drug into a Self-Nano Emulsifying Drug Delivery System (SNEDDS) using an indigenous natural lipophile extracted from sesame seeds via cool press. SNEDDS based on the pure indigenous natural lipophile and also blends of the natural lipophile with commercially available modified oil (labrafac CC) were formulated and their application in improving the delivery of Artemether was evaluated. Pseudo ternary phase diagram construction was carried out to identify stable formulations. Stable combinations from the phase diagram were loaded with Artemether and characterized with respect to globule size, Poly Dispersity Index (PDI), viscosity, drug-excipients compatibility and stability, emulsification time, drug loading efficiency, in vitro drug release, infinite aqueous dilution, post dilution drug precipitation and in vivo anti-malarial performance in Swiss male mice infected with lethal strain of Plasmodium berghei. The optimized SNEDDS had mean globule size of less than 50.0 nm, showed excellent emulsification time of less than a minute, promoted fast drug release, exhibited no phase separation and demonstrated the highest antimalarial activity. The oil component of the formulation contributed most significantly (P<0.05) to droplet size variations. The result highlighted the potential application of indigenous natural lipophile in the development of a nano drug carrier for the efficient delivery of Artemether, which can be applicable for other Bio pharmaceutics classification system class II and IV drugs exhibiting identical biopharmaceutical challenges.

Biography:

Abstract:

An OPD  questionnaire based study was carried out to assess prevalence of use of Thermometer by parents of children with fever.

Parents coming to the OPD of the Pediatrics department of  two  Medical colleges in Jaipur(Rajasthan, INDIA) were interviewed regarding use of thermometer at home in case their child was having fever prior to bringing the patient to the doctor.

A questionnaire was filled after taking their consent and anonymity of the patient and caregivers was maintained. A total of 240 parents were interviewed.

After the questionnaire they were educated on the use of the thermometer

Results showed that nearly 90 percent parents were not using the thermometer prior to bringing their child to a pediatrician with complaints of fever.

Biography:

Mr Samarth Sahai is studying 3rd semester M.B.B.S at  Mahatma Gandhi Institute of Medical Sciences,Jaipur, India.

Abstract:

Mothers of newborns were interviewed regarding common practices being carried out by them and their logic behind using knives, matches etc to protect their newborns. We discussed how they can actually protect their baby through early and exclusive breast feeding, immunization and proper care and protection from mosquitoes. This exercise also made the young mothers question every practice and understand logic behind it rather than blindly follow them and gave them confidence that they have a right to question and do away with illogical practices

This study was done to initiate a healthy discussion in the post natal wards by the undergraduate medical students posted in Obstetrics and Gynaecology with the mothers who have delivered newborns in the last 72 hours. This discussion is a small step in awareness generation of ways  to bring down the high neonatal mortality by  tapping the most important link in the primary health care providing system i.e. the mother.  The study was carried out in the post natal wards of the Obstetrics department of two medical colleges in urban areas of Rajasthan (INDIA)

Biography:

Ning Li has completed her M.D. in 2009 from University of Geneva, Switzerland, where she obtained her postdoctoral training focusing on metabolic disorders. After 4- year working at Chinese Academy of Medical Sciences and Peking Union Medical College, Ning Li is currently the associated professor of China Academy of Chinese metabolic diseases, mitochondrial function and dysfunction, and host metabolism in viral infection.

Abstract:

Atherosclerosis (AS) is a leading cause of death and loss of productive

life worldwide. The immature form of High-density lipoprotein (HDL)

has been shown advantageous in improving plaque targeting and antiAS

efficacy. However, the prohibitive cost of ApoA-I protein used to

generate functional HDL and the time-consuming procedure of HDL

synthesis impeded its clinical application. Though HDL mimic peptides

are capable of fulfilling HDL function with a dramatic low-cost, their

instability in vivo failed to put their utilization into practice. Our current

study was designed to synthesize peptide-based HDL (pHDL) in order

to increase in vivo stability of peptides by incorporating with

phospholipids. PHDL produced by microfluidics resulted in discoidal

nano-scale particles, showing of 37.8 nm diameter, 0.275 PdI and -4.17

mV zeta potential. Using in vivo imaging system, FITC-labeled pHDL

was highly recruited to the aorta of AS model ApoE-/- mice compared

to C57BL/6 control mice，24 hrs post-intraperitoneal injection.

Intraperitoneal administration of pHDL to ApoE-/- mice twice per week

for 12 weeks reduced more than 40% plasma TG, TC and LDL-C, which

leads to 40% reduction of aortic plaques. In addition, increase of

plasma ALT, AST and creatinine in ApoE-/- mice were largely

improved by pHDL treatment, indicating a general protective effect of

pHDL. In conclusion, pHDL represents an affordable alternative of

HDL, in terms of plaque-targeting and anti-AS effects.

Biography:

Ruodan Xu has completed her PhD with cancer biology in 2010 from University of Copenhagen. Afterwards, she continued her postdoc in Geneva University, Cologne University and Aarhus University for studies on stem cells and tissue engineering. Currently, she is the associate professor of China Academy of Chinese Medicine Science. She has published more than 19 papers in reputed journals and has been serving as reviewers for many reputed journals. Her research interests focus on regenerative medicine, nanomedicine targeted elderly chronic disease including atherosclerosis and Alzheimer’s disease.

Abstract:

Scarcity and damaged fibroblasts is one cause of impaired healing. We

developed a novel 3D biomimetic scaffold for stem cells augmentation

and differentiation to fibroblasts. The 3D scaffold PFPC-C in this

study was prepared using electrospun PCL/Col1 fibers which

embedded in PEG-fibrinogen (PF) hydrogel and infiltrated with

connective tissue growth factor (CTGF). In vitro, PFPC-C scaffold

showed good biocompatibility confirmed by the human induced

pluripotent stem cells derived mesenchymal stem cells (hiPS-MSCs)

attachment, infiltration, and proliferation throughout the construct.

CTGF loaded in this scaffold were sustained released and hiPS-MSCs

coultured on the scaffolds showed stronger fibroblastic commitment.

The performance of the scaffold was further evaluated in vivo. PFPC-C

scaffolds seeded with or without hiPS-MSCs were implanted in the rat

muscle injury model. 4 weeks, 12 weeks and 6 months later the mice

were sacrificed respectively, the grafted implants were analyzed with

histologic and mechanical examinations. Our results showed this 3D

scaffold provided a suitable environment and well fibroblasts

differentiation from hiPS-MSCs. This 3D scaffold could be potentially

used in cell-based therapies for connective tissue related disorders.

Biography:

Philip James is a marketing and communications consultant to the medical and architecture industries. Philip is an expert at building narratives and personal brands. His clients include hospitals, physicians, and industry associations. He has worked at ENDO, and the World Congress on Thyroid Cancer.

Abstract:

In this case, branding isn’t necessarily about logos and taglines. Simply put, a physician’s brand is essentially equal to his or her reputation. What patients think about you, how well-known you are in your community, your online presence–that is your brand. More and more patients are turning to online sources to find a physician. They may look at your website, but they are also likely consulting online reviews and listings as well. Branding is more important than ever if you want to attract the attention of these patients, whether you are just starting out or are already an established physician. During this session, the following topics will be covered:

1. Five steps to brand building

2. How to use digital tools and social platforms

3. The danger of doing nothing

4. Case Study: Dr. Netterville